Course Syllabus

OUR LADY OF FATIMA UNIVERSITY

COLLEGE OF MEDICINE

MICROSCOPIC HUMAN STRUCTURAL BIOLOGY

I. COURSE CODE

               

            Microscopic HSB is an annual subject given to first year medical students with 4 hours lectures and 4 hours laboratory per week for a total of 10 units/year. It is divided into three sub-disciplines – Histology, Embryology and Neuroanatomy. Following horizontal integration of subjects in the 1st year, all three sub-disciplines are discussed synchronously with the other major first year subjects (Biochemistry and Physiology) in relation to a body system together with their clinical correlation.

            In Histology, the normal microscopic features of the cells, tissues and organs are discussed and viewed under the light microscope. Included in the discussion are the parenchymal cells, stroma, and characteristic histologic features of the different organs of the body. Embryonic development of the tissues and organs are included in the discussion prior to the histological structures to enable the students to appreciate their development and correlate normal development with abnormalities in the course of development. Under the light microscope, an actual cut section of a pig embryo is made available for demonstration and individual viewing of the students.

           Neuroanatomy involves the study of major macroscopic and microscopic components of the central and peripheral nervous system. Preserved specimens of the cerebrum, cerebellum and brainstem are available for students to study in the laboratory. These specimens are eventually cut, to locate the different internal features. In addition, sensory and motor pathways are traced and illustrated. Common neurologic conditions are also introduced to the students.

            Selected clinical cases involving different organ systems of the body are prepared for the students. Consultants from the clinical departments will give a short lecture relevant to these cases. This is followed by the discussion of the specific abnormalities, congenital malformations, as well as neurological defects as the case may require. Correlating the normal and the abnormal structures, and its clinical manifestations as early as the first year will enable the first year students to develop a solid foundation that will help them in their future clinical subjects and eventual clinical practice.

 

VIII. GENERAL OBJECTIVES:

            At the end o the course, the students would demonstrate sufficient knowledge and skills in discussing the normal microscopic morphologic features of normal cells, tissues, and organs of the human body. The students can also correlate these morphologic features with the embryonic development of the organs in relation to the germ layers, anlage and fates of the different parts of the body. In Neuroanatomy, students can correlate the normal structures and functions of the nervous system together with the neurological pathway with common neurologic conditions and their manifestations. In all these  sub-disciplines, the students are expected at the end of the course to apply all anatomical information to clinical setting and integrate these information with the other disciplines, Physiology and Biochemistry.

 

 

 

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                      CELLULAR STRUCTURES AND FUNCTIONS

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Differences between prokaryotic cell and  eukaryotic cell

2 hours lecture

Didactic lecture with powerpoint presentations

Short Quiz

1. differentiate prokaryotes from

2. Principal parts of the cell

2 hours laboratory

 

Unit Quiz

eukaryotes.

    2.1. Cell membrane

 

Clinical Correlation

 

2. describe the principal parts of the cell.

    2.2. Cytoplasmic organelles

 

 

Prelim Exam

3. describe the different specialized

          2.2.1. Mitochondria

 

Random Recitation

 

structures/specializations of the cell.

          2.2.2. Endoplasmic Reticulum

 

 

Midterm Exam

4. discuss the methods on how the cell

          2.2.3. Golgi Apparatus

 

Laboratory exercises with

 

divides and its associated anomalies.

          2.2.4. Lysosomes

 

slide orientation using

Final Exam

5. name some structural and functional

          2.2.5. Peroxisomes

 

videoflex and iPad

 

abnormalities of the cell.

          2.2.6. Phagosomes

 

 

Practical Exams

 

          2.2.7. Cytoskeleton

 

Small group discussions

 

 

    2.3. Role of nucleus and what it is made up of

 

 

 

 

3. Specialized structures/specialization found

 

 

 

 

  in the cell.

 

 

 

 

    3.1. Cilia

 

 

 

 

    3.2. Sterocilia

 

 

 

 

    3.3. Microvili

 

 

 

 

4. Phases of cell division

 

 

 

 

5. Selected cellular abnormalities

 

 

 

 

    5.1. Kartagener's Syndrome

 

 

 

 

    5.2. Trisomy 21

 

 

 

 

    5.3 Klinefelter's Syndrome

 

 

 

 

    5.4. Turner's Syndrome

 

 

 

  1. COURSE CONTENT

 

 

 

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                      PARENCHYMA, STROMA, INTERCELLULAR SPACES AND CONTENTS, CELL CHARACTERISTIC

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Definition of parenchyma

 

Didactic lecture with

Short Quiz

 

2. Parenchyma of different organs

2 hours lecture

powerpoint presentations

 

1. define "parenchyma"

    2.1. Parenchyma of the cerebrum

 

 

Unit Quiz

2. explain the role of parenchyma, citing

    2.2. Parenchyma of the heart

2 hours laboratory

Clinical Correlation

 

examples in each of the organs.

    2.3. Parenchyma of the stomach

 

 

Prelim Exam

3. define "stroma"

    2.4. Parenchyma of the lymph node

 

Random Recitation

 

4. explain the role of the stroma, citing

    2.5. Parenchyma of the thyroid

 

 

Midterm Exam

examples in each of the organs

3. Definition of stroma

 

Laboratory exercises with

 

5. give the basis of characterizing cells,

4. Stroma of different organs

 

slide orientation using

Final Exam

citing examples of each.

    4.1. Stroma of the heart

 

videoflex and iPad

 

6. discuss the intercellular spaces and its

    4.2. Stroma of the stomach

 

 

Practical Exam

 contents

    4.3. Stroma of the cerebrum

 

Small group discussions

 

 

    4.4. Stroma of the lymph node

 

 

 

 

5. Characteristics of cells

 

 

 

 

    5.1. Size

 

 

 

 

    5.2. Shape

 

 

 

 

    5.3. Number of nucleus

 

 

 

 

    5.4. Location of nucleus

 

 

 

 

6. Contents of intercellular spaces

 

 

 

 

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                      NERVOUS TISSUE:                            Central Nervous System

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Parts of the cerebrum

 

Didactic lecture with

Short Quiz

1. describe the cerebrum and its parts

    1.1. Layers of the cerebrum

2 hours lecture

powerpoint presentations

 

in relation to:

           1.1.1 Molecular layer

 

 

Unit Quiz

    1.1. the different layers of the cerebrum

           1.1.2. Outer granular layer

2 hours laboratory

Clinical Correlation

 

          its cellular components

    1.2. Distribution, relation and features of the

 

 

Prelim Exam

    1.2. the distribution, relation and features

           white substances of the cerebrum

 

Random Recitation

 

          of its white substance.

    1.3. Distribution, relation and features of the

 

 

Midterm Exam

    1.3. the distribution, relation and features

          gray substance of the cerebrum

 

Laboratory exercises with

 

          of its gray substances.

    1.4. Supporting structures/cells

 

slide orientation using

Final Exam

    1.4. its supporting structures

           1.4.1. Neuroglial and other supporting

 

videoflex and iPad

 

2. describe the cerebellum and its parts in

                     cells

 

 

Practical Exam

relation to:

           1.4.2. Meninges

 

Small group discussions

 

    2.1. the different layers of the cerebellum

2. Parts of the cerebellum

 

 

 

          its cellular components.

    2.1. Layers of the cerebellum

 

 

 

    2.2. the distribution, relation and features

           2.1.1. Molecular layer

 

 

 

          of its gray substance.

           2.1.2. Layer of Purkenji cells

 

 

 

    2.3. the distribution, relation and features

           2.1.3. Granular layer

 

 

 

          of its white substances.

    2.2. Distribution, relation and features of the

 

 

 

 

           gray substance of the cerebellum

 

 

 

 

    2.3. Distribution, relation and features of the

 

 

 

 

           white substance of the cerebellum

 

 

 

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                      NERVOUS TISSUE:                           Peripheral  Nervous Sytem

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Nerve

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Connective tissue covering

 

powerpoint presentations

 

1. describe the nerve as to its connective

    1.2. Classification

2 hours laboratory

 

Unit Quiz

tissue coverings and parts

    1.3. Difference between dendrite and axon

Clinical Correlation

 

2. differentiate axon from dendrite

2. Components of the blood brain barrier

 

 

Prelim Exam

3. compare the different types of nerves.

3. Formation of myelin sheath

 

Random Recitation

 

4. illustrate the blood-brain barrier.

4. Ganglion

 

 

Midterm Exam

5. describe the formation of myelin sheath.

    4.1. Components of a ganglion

 

Laboratory exercises with

 

6. describe a ganglion and its components

    4.2. Types of ganglia

 

slide orientation using

Final Exam

7. compare the different types of ganglia.

    4.3. Characteristics of the different types of

 

videoflex and iPad

 

 

          ganglia

 

 

Practical Exams

 

 

 

Small group discussions

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                      MUSCLE TISSUE:                          

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Types of muscle tissue

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Skeletal muscle

 

powerpoint presentations

 

1. characterized the three types of muscle

    1.2. Cardiac muscle

2 hours laboratory

 

Unit Quiz

    tissue.

    1.3. Smooth muscle

Clinical Correlation

 

2. describe the structures in the muscle fiber

4. Structures in the muscle fiber

 

 

Prelim Exam

 

    2.1. Sarcomere

 

Random Recitation

 

 

    2.2. T-tubular system

 

 

Midterm Exam

 

    2.3. Myosin

 

Laboratory exercises with

 

 

    2.4. Actin

 

slide orientation using

Final Exam

 

 

videoflex and iPad

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                      SENSORY AND MOTOR NERVE ENDINGS                           

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Sensory nerve endings

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Free nerve endings

 

powerpoint presentations

 

1. describe the different sensory nerve

    1.2. Merkel's corpuscle

2 hours laboratory

 

Unit Quiz

endings for general sensations found in

    1.3. Meissner's corpuscle

Clinical Correlation

 

 the skin.

    1.4. Golgi Mazzoni corpuscle

 

 

Prelim Exam

2. describe the sensory nerve endings found

    1.5. Pacinian corpuscle

 

Random Recitation

 

 in the skeletal muscles, tendons, and joints.

    1.6. Genital corpuscle

 

 

Midterm Exam

3. describe the structures found at the motor

    1.7. Ruffini's corpuscle

 

Laboratory exercises with

 

end plate or neuromuscular junction.

    1.8. Krause end bulb

 

slide orientation using

Final Exam

4. describe the contraction of skeletal

    1.9. Muscle spindle

 

videoflex and iPad

 

muscles through the motor end plate.

    1.10. Golgi tendon

 

 

Practical Exams

 

2. Motor nerve endings in skeletal muscle

 

Small group discussions

 

 

    2.1. Motor end plate

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                      RECEPTORS AND EFFECTORS

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Forms of sensory receptors

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Mechanoreceptors

 

powerpoint presentations

 

1. describe the special organs that lie at the

    1.2. Thermo receptors

2 hours laboratory

 

Unit Quiz

end of sensory and motor nerve endings.

    1.3. Nocireceptors

Clinical Correlation

 

2. characterize the different forms of

    1.4. Electromagnetic receptors

 

 

Prelim Exam

sensory receptors.

    1.5. Chemoreceptors

 

Random Recitation

 

3. discuss the types of motor fibers.

2. Types of motor fiber

 

 

Midterm Exam

 

    2.1. large alpha myelinated

 

Laboratory exercises with

 

 

    2.2. Small gamma myelinated fibers

 

slide orientation using

Final Exam

 

    2.3. Fine unmyelinated fibers

 

videoflex and iPad

 

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

 

 

 

 

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                      FUNDAMENTAL TYPE OF TISSUES: Epithelial Cells and Tissues

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Fundamental types of tissues

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Epithelial

 

powerpoint presentations

 

1. describe the four fundamental types of

    1.2. Connective

2 hours laboratory

 

Unit Quiz

tissues.

    1.3. Muscular

Clinical Correlation

 

2. differentiate the epithelial tissues and its

    1.4. Nervous

 

 

Prelim Exam

subtypes.

2. Subtypes of epithelial tissues

 

Random Recitation

 

3. describe the different junctional

    2.1. Simple epithelium

 

 

Midterm Exam

complexes.

    2.2. Pseudostratified epithelium

 

Laboratory exercises with

 

 

    2.3. Stratified epithelium

 

slide orientation using

Final Exam

 

    2.4. Transitional epithelium

 

videoflex and iPad

 

 

3. Junctiona complexes

 

 

Practical Exams

 

    3.1. Zonula occludens

 

Small group discussions

 

 

    3.2. Zonula adherens

 

 

 

 

    3.3. macula adherens

 

 

 

 

    3.4. Nexus

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                      FUNDAMENTAL TYPE OF TISSUES: Connective Tissues

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Fundamental components of connective tissues

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Connective tissue cells

powerpoint presentations

 

1. describe the fundamental components

    1.2. Connective tissue fibers

2 hours laboratory

 

Unit Quiz

of connective tissues.

    1.3. Ground substance

Clinical Correlation

 

2. characterize the subtypes of connective

2. Subtypes of connective tissues

 

Prelim Exam

tissues.

    2.1. Fibrous

Random Recitation

 

3. compare the different types of

    2.2. Adipose

 

Midterm Exam

connective fibers.

    2.3. Mesenchymal

Laboratory exercises with

 

 

    2.4. Mucous connective tissue

slide orientation using

Final Exam

 

    2.5. Myeloid

videoflex and iPad

 

 

    2.6. Bone

 

Practical Exams

 

    2.7. Cartilage

Small group discussions

 

 

3. Type of connective fibers

 

 

 

    3.1. Collagenous

 

 

 

    3.2. Elastic

 

 

 

    3.3. Reticular

 

 

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                      DEVELOPMENT OF BONES AND CARTILAGES

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1.Types of bone development

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Intramembranous bone formation.

powerpoint presentations

 

1. differentiate the types of bone.

    1.2. Endochondral bone formation.

2 hours laboratory

 

Unit Quiz

2. compare the two patterns of bone

2. Types ossification centers

Clinical Correlation

 

ossification.

    2.1. Primary ossification center

 

Prelim Exam

3. describe the formation of the

    2.2. Secondary ossification center

Random Recitation

 

anal skeleton.

3. Components of the axial skeleton

 

Midterm Exam

4. illustrate the formation of the

    3.1. Vertebral column

Laboratory exercises with

 

appendicular skeleton.

    3.2. Ribs

slide orientation using

Final Exam

 

    3.3. Sternum

videoflex and iPad

 

 

    3.4. Skull

 

Practical Exams

 

4. Components of the appendicular skeleton

Small group discussions

 

 

    4.1. Pectoral and pelvic girdle

 

 

 

    4.2. Upper and lower limbs

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                      BONES AND CARTILAGES

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Forms of cartilages

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Hyaline cartilages

powerpoint presentations

 

1. compare the properties of the different

    1.2. Elastic cartilages

2 hours laboratory

 

Unit Quiz

types of cartilages

    1.3. Fibrous cartilages

Clinical Correlation

 

2. compare the histologic components

2. Forms of bones

 

Prelim Exam

of the different types of bones.

    2.1. Compact bone

Random Recitation

 

 

    2.2. Spongy bone

 

Midterm Exam

 

 

Laboratory exercises with

 

 

 

slide orientation using

Final Exam

 

 

videoflex and iPad

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                      EXTERNAL AND INTERNAL FEATURES OF THE SPINAL CORD

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. External features of the spinal ord

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Investing membrane of the spinal cord

powerpoint presentations

 

1. describe the external features of the

    1.2. Enlargements of the spinal cord

2 hours laboratory

 

Unit Quiz

spinal cord

    1.3. Segments of the spinal cord

Clinical Correlation

 

2. describe the internal features of the

2. Internal features of the spinal cord

 

Prelim Exam

spinal cord

    2.1 Gray matter

Random Recitation

 

3. illustrate the fiber tracts in the white

    2.2. White matter

 

Midterm Exam

matter of the spinal cord.

3. Fiber tracts in the spinal cord

Laboratory exercises with

 

 

    3.1 Ascending tracts

slide orientation using

Final Exam

 

    3.2. Descending tracts

videoflex and iPad

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                      AUTONOMIC NERVOUS SYTEM

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1.Subdivision of the autonomic nervous system

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Sympathetic  division

powerpoint presentations

 

1. discuss the subdivisions of the

    1.2. Parasympathetic division

2 hours laboratory

 

Unit Quiz

Autonomic Nervous System.

2. Functions of the autonomic nervous system

Clinical Correlation

 

2. describe the functions of the

    2.1. Center of functions of target tissues

 

Prelim Exam

Autonomic Nervous System.

    2.2. Homeostasis

Random Recitation

 

3. explain the manifestations of common

3. Autonomic ganglia found I the haed of

 

Midterm Exam

clinical conditions associated with

region

Laboratory exercises with

 

dysfunction of the autonomic nervous

4. Ciliary ganglion

slide orientation using

Final Exam

system.

    4.1. Pterygopalatine ganglion

videoflex and iPad

 

 

    4.2. Otic ganglion

 

Practical Exams

 

5. Common clinical conditions associated with

Small group discussions

 

 

disorders of the autonomic nervous system

 

 

 

    5.1. Spinal sitocil

 

 

 

    5.2. Hirschsprung's Disease

 

 

 

    5.3. Horner's Syndrome

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                      SENSORY AND MOTOR NEURONS OF THE CNS

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1.Sensory neurons of the central nervous

2 hours lecture

Didactic lecture with

Short Quiz

 

 system

powerpoint presentations

 

1. categorize the sensory neurons of the

   1.1 General somatic afferent neurons

2 hours laboratory

 

Unit Quiz

Central Nervous System

   1.2 General visceral afferent neurons

Clinical Correlation

 

2. characterize the motor neurons of the

   1.3 Special visceral afferent neurons

 

Prelim Exam

Central Nervous System

   1.4 Special somatic afferent neurons

Random Recitation

 

3. describe the association neurons of the

2. Motor neurons of the central nervous system

 

Midterm Exam

nervous system.

   2.1 General somatic afferent neurons

Laboratory exercises with

 

 

   2.2 General visceral afferent neurons

slide orientation using

Final Exam

 

   2.3 Special visceral afferent neurons

videoflex and iPad

 

 

3. Association neurons located with

 

Practical Exams

 

   3.1 Cerebral cortex

Small group discussions

 

 

   3.2 Cerebellar cortex

 

 

 

   3.3 Basal ganglia

 

 

 

   3.4 Diencephalon

 

 

 

   3.5 Brainstem

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                      DEVELOPMENT OF THE DIGESTIVE TRACT

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Divisions of the developing digestive tract

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Foregut

powerpoint presentations

 

1. describe the divisions of the developing

    1.2. Midgut

2 hours laboratory

 

Unit Quiz

digestive tract.

    1.3 Hingut

Clinical Correlation

 

2. describe the development of the

2. Derivatives of the foregut

 

Prelim Exam

derivatives at the:

    2.1. Pharynx

Random Recitation

 

     2.1 foregut.

    2.2. Esophagus

 

Midterm Exam

     2.2 midgut.

    2.3. Dorsal pancreatic bud

Laboratory exercises with

 

     2.3 hindgut.

    2.4. Hepatic diverticulum

slide orientation using

Final Exam

3. describe common congenital anomalies

    2.5. Stomach

videoflex and iPad

 

of the digestive system.

    2.6. Small intestine

 

 

Practical Exams

 

 

 

3. Derivatives of the midgut

 

Small group discussions

 

 

    3.1. Small intestine

 

 

 

    3.2. Large intestine

 

 

 

4. Derivatives of the hindgut

 

 

 

    4.1. Small intestine

 

 

 

    4.2. Large intestine

 

 

 

5. Common congenital anomalies of the digestive

 

 

 

system

 

 

 

    5.1. Pyloric stenosis

 

 

 

    5.2. Biliary atresia

 

 

 

    5.3. Megacolon

 

 

 

    5.4. Imperforate anus

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                      ACCESSORY ORGANS OF DIGESTION: Liver, Gallbladder and Pancreas

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Histologic characteristic of the liver

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Distribution of connective tissue in the

powerpoint presentations

 

1. discuss the histologic characteristics of

           liver

2 hours laboratory

 

Unit Quiz

the liver and their functional significance.

    1.2. Characteristic of the liver lobule

Clinical Correlation

 

2. describe the general histology of the

    1.3 Topographical relationship of the hepatic

 

Prelim Exam

gallbladder and extra-hepatic bile ducts.

         cell to the vascular and biliary system of

Random Recitation

 

3. discuss the genral histology of the

          the liver

 

Midterm Exam

pancreas.

    1.4. Functional significance of the hepatic

Laboratory exercises with

 

4. give the role of the various accessory

          sinusoids

slide orientation using

Final Exam

organs in digeation.

    1.5. Components of the intrahepatic biliary

videoflex and iPad

 

 

           system

 

Practical Exams

 

2. Characteristics of the general histology of the

 

 

 

gallbladder and extra-hepatic bile ducts

 

 

 

 

 

 

 

 

 

    2.1. Layers of the gallbladder wall

 

 

 

 

    2.2. Histologic characteristics of the layers of

 

 

 

          the gallbladder wall

 

 

 

    2.3. Microscopic features of the extra-hepatic

 

 

 

          ducts

 

 

 

3. General histology of the pancreas

 

 

 

    3.1. nature of the connective tissue of the

 

 

 

           pancreas

 

 

 

    3.2. Endocrine and exocrine portions of the

 

 

 

           pancreas

 

 

 

    3.3. Cytological components of the islet of

 

 

 

          Langerhans

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                           ORAL CAVITY

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. General histology of the oral cavity and its

2 hours lecture

Didactic lecture with

Short Quiz

 

    associated structural

powerpoint presentations

 

1. describe the general histology of the oral

    1.1. Epithelial lining of the oral cavity and the

2 hours laboratory

 

Unit Quiz

cavity and its associated structures.

           muscle type on its wall

Clinical Correlation

 

2. compare the different salivary glands as

    1.2. Different structures seen within the oral

 

Prelim Exam

to histologic features and type of secretion

           cavity

Random Recitation

 

 

2. Major salivary glands

 

Midterm Exam

 

    2.1. Parotid

Laboratory exercises with

 

 

    2.2. Submandibular

slide orientation using

Final Exam

 

    2.3. Sublingual

videoflex and iPad

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                  ESOPHAGUS AND STOMACH

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Esophagus

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1 Layers

powerpoint presentations

 

1. describe the histologic features of the

        1.1.1 Mucosa

2 hours laboratory

 

Unit Quiz

esophagus.

        1.1.2. Submucosa

Clinical Correlation

 

2. discuss the general histology of the

        1.1.3. Tunica muscularis

 

Prelim Exam

stomach and the functional significance

        1.1.4. Tunica adventitia

Random Recitation

 

of the cells found in the different layers.

     1.2. Functional role of structures/cells

 

Midterm Exam

 

           in each layer

Laboratory exercises with

 

 

2. Stomach

slide orientation using

Final Exam

 

    2.1. Layers

videoflex and iPad

 

 

        2.1.1 Mucosa

 

Practical Exams

 

        2.1.2. Submucosa

Small group discussions

 

 

        2.1.3. Tunica muscularis

 

 

 

        2.1.4. Tunica serosa

 

 

 

    2.2. Functional role of structures/cells

 

 

 

           in each  layer

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                     SMALL INTESTINE, LARGE INTESTINE AND APPENDIX

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Segments of the small intestine

2 hours lecture

Didactic lecture with

Short Quiz

 

     1.1. Duodenum

powerpoint presentations

 

1. characterize the segments of the small

     1.2. Jejunum

2 hours laboratory

 

Unit Quiz

intestines.

     1.3. Ileum

Clinical Correlation

 

2. give the functional significance of the

2. Special structures in the small intestine

 

Prelim Exam

special structures and special cells found

     2.1. Microvilli

Random Recitation

 

in the small intestines.

     2.2. Villi

 

Midterm Exam

3. discuss the special types of cells in

     2.3. Plica circulars

Laboratory exercises with

 

small intestine.

     2.4. Glands of Lieberkuhn

 

slide orientation using

Final Exam

 

 

4. characterize the segments of the

     2.5. Brunner's patch

 

videoflex and iPad

 

large intestine and the special structures

     2.6. Peyer's patch

 

Practical Exams

found in the colon.

3. Special cells in the small intestine

Small group discussions

 

 

     3.1. Paneth cell

 

 

 

     3.2. M- cell

 

 

 

     3.3. Enterochromattin cell

 

 

 

4. Segments of the large intestine

 

 

 

     4.1. Cecum

 

 

 

     4.2. Ascending colon

 

 

 

     4.3. Transverse colon

 

 

 

     4.4. Descending colon

 

 

 

     4.5. Sigmoid colon

 

 

 

     4.6. Rectum

 

 

 

     4.7. Anus

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                    MYELOID TISSUE

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Types of Bone Marrow

2 hours lecture

Didactic lecture with

Short Quiz

 

     1.1. Red marrow

powerpoint presentations

 

1. differentiate the two types of bone

     1.2. Yellow marrow

2 hours laboratory

 

Unit Quiz

marrow.

2. Phases of hematopoeisis

Clinical Correlation

 

2. describe the phases of hematopoiesis

     2.1. Mesoblastic phase

 

Prelim Exam

3. describe the stages of erythropoeisis

     2.2. Hepatic phase

Random Recitation

 

4. describe the stages of granulocytopoeisis

     2.3. Myeloid phase

 

Midterm Exam

5. describe the stages of monocytopoeisis

3. Stages in erythropoeisis

Laboratory exercises with

 

6. describe the stages of lymphopoeisis

     3.1. Proerythroblast

slide orientation using

Final Exam

7. describe the stages in thrombopoeisis

     3.2. Basophilic erythroblast

 

videoflex and iPad

 

 

 

 

 

     3.3. Polychromatophilic erythroblast

 

 

Practical Exams

 

     3.4. Orthochromatophilic erythroblast

Small group discussions

 

 

     3.5. Reticulocyte

 

 

 

     3.6. Mature erythrocytes

 

 

 

4. Stages of granulocytopoeisis

 

 

 

     4.1. Myoblast

 

 

 

     4.2. Promyelocyte

 

 

 

     4.3. Myelocyte

 

 

 

     4.4. Metamyelocyte

 

 

 

     4.5. Bands

 

 

 

     4.6. Mature granulocyte

 

 

 

5. Stages of monocytepoeisis

 

 

 

     5.1. Monoblast

 

 

 

     5.2. Promonocyte

 

 

 

     5.3. Monocyte

 

 

 

6. Stages of lymphopoeisis

 

 

 

     6.1. Lymphocyte

 

 

 

     6.2. Prolymphocyte

 

 

 

     6.3. Lymphocyte

 

 

 

7. Stages in thrombopoeisis

 

 

 

     7.1. Megakaryoblast

 

 

 

     7.2. Megakaryocyte

 

 

 

     7.3. Thrombocyte

 

 

 

 

 

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                      BLOOD AND LYMPH

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Composition

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Plasma

powerpoint presentations

 

1. discuss blood and its composition.

    1.2. Plasma protein

2 hours laboratory

 

Unit Quiz

2. describe the lymph and its components.

    1.3. Red blood cells

Clinical Correlation

 

 

    1.4. White blood cells

 

Prelim Exam

 

    1.5. Platelets

Random Recitation

 

 

2. Components of the lymph

 

Midterm Exam

 

    2.1. Fluid

Laboratory exercises with

 

 

    2.2. Cells

slide orientation using

Final Exam

 

    2.3. Lipids

videoflex and iPad

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                      LYMPHATIC TISSUES AND ORGANS

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Components of the lymphatic system

2 hours lecture

Didactic lecture with

Short Quiz

 

   1.1. Cells

powerpoint presentations

 

1. describe the components lymphatic

   1.2. Tissues

2 hours laboratory

 

Unit Quiz

system.

   1.3. Organs

Clinical Correlation

 

2. compare the microscopic morphology

2. Organs of the lymphatic system

 

Prelim Exam

of the different organs of the lymphatic

   2.1. Tonsils

Random Recitation

 

system.

   2.2. Thymus

 

Midterm Exam

 

   2.3. Lymph nodes

Laboratory exercises with

 

 

   2.4. Spleen

slide orientation using

Final Exam

 

   2.5. Peyer's patch

videoflex and iPad

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                        IMMUNE SYSTEM

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Cells of the immune system

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Lymphocytes

powerpoint presentations

 

1. describe the cells of the immune system.

    1.2. Macrophages

2 hours laboratory

 

Unit Quiz

2. compare the different classes of

    1.3. Blood phogocytes

Clinical Correlation

 

immunoglobulins

2. Classes of immunoglobulins

 

Prelim Exam

3. describe the classification of immunity

    2.1. IgG

Random Recitation

 

based on how antibodies are acquired.

    2.2. IgM

 

Midterm Exam

4. discuss common clinical conditions

    2.3. IgA

Laboratory exercises with

 

associated with immune disorder.

    2.4. IgD

slide orientation using

Final Exam

 

    2.5. IgE

videoflex and iPad

 

 

3. Classification of immunity based on how

 

Practical Exams

 

embodies are acquired

Small group discussions

 

 

    3.1. Natural active

 

 

 

    3.2. Natural passive

 

 

 

    3.3. Artificial active

 

 

 

    3.4. Artificial passive

 

 

 

4. Common clinical condition associated with

 

 

 

immune disorder

 

 

 

    4.1. Acquired immunodeficiency syndrome

 

 

 

    4.2. Thymic aplasia

 

 

 

    4.3. Hypersensitivity reactions

 

 

 

 

 

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                      DEVELOPMENT OF THE CARDIOVASCULAR SYSTEM: Heart and Blood Vessels

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Parts of the heart arising from the endocardial

2 hours lecture

Didactic lecture with

Short Quiz

heart tubes

powerpoint presentations

 

1. Describe the different parts of the heart

    1.1. Ventricle

2 hours laboratory

 

Unit Quiz

developing from the endocardiac heart tube.

    1.2. Atrium

Clinical Correlation

 

2. illustrate blood flow in common

    1.3. Cardiac valves

 

Prelim Exam

congenital heart anomalies.

2. Common congenital heart anomalies

Random Recitation

 

3. describe the formation of the major

    2.1. Ventricular septal

 

Midterm Exam

arteries and veins

    2.2. Atrial septal defect

Laboratory exercises with

 

4. describe the fate of the blood vessels in

    2.3. Tetralogy of Fallot

slide orientation using

Final Exam

the umbilical cord.

3. Formation of the major arteries

videoflex and iPad

 

 

    3.1.  Aorta

 

Practical Exams

 

    3.2. Brachiocephalic artery

Small group discussions

 

 

    3.3. Subclavian artery

 

 

 

4. Formation of the major veins

 

 

 

     4.1. Superior vena cava

 

 

 

     4.2. Inferior vena cava

 

 

 

     4.3. Innominate vein

 

 

 

     4.4. Subclavian vein

 

 

 

5. Blood vessels of the umbilical cord

 

 

 

     5.1. Umbilical artery

 

 

 

     5.2. Umbilical vein

 

 

 

 

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            HEART AND BLOOD VESSELS

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Major histological structures of the heart

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Pericardium

powerpoint presentations

 

1. discuss the histologic features of the

    1.2. Myocardium

2 hours laboratory

 

Unit Quiz

major structures of the heart.

    1.3. Endocardium

Clinical Correlation

 

2. illustrate the conducting system of the

2. Conducting system of the heart

 

Prelim Exam

heart

3. Histologic layers of the blood vessels, arteries,

Random Recitation

 

3. compare the histologic layers of the

capillaries and veins

 

Midterm Exam

arteries, capillaries, arterioles, and veins.

    2.1. tunica externa

Laboratory exercises with

 

 

    2.2. Tunica media

slide orientation using

Final Exam

 

    2.3. Tunica intima

videoflex and iPad

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

LEARNING OBJECTIVES

LEARNING CONTENT                            DEVELOPMENT OF THE SKIN AND ITS DERIVATIVES

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Layers of the skin

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Epidermis

powerpoint presentations

 

1. describe the events in the development

    1.2. Dermis

2 hours laboratory

 

Unit Quiz

of the layers of skin

2. Appendages of the skin

Clinical Correlation

 

2. describe the development of the

    2.1. Hair

 

Prelim Exam

appendages of the skin

    2.2. Nail

Random Recitation

 

 

    2.3. Sebaceous gland

 

Midterm Exam

 

    2.4. Sweat gland

Laboratory exercises with

 

 

    2.5. Mammary gland

slide orientation using

Final Exam

 

    2.6. Teeth

videoflex and iPad

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            INTEGUMENTARY SYSTEM

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Two main layers of the skin

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Epidermis

powerpoint presentations

 

1. differentiate the two main layers of the

    1.2. Dermis

2 hours laboratory

 

Unit Quiz

skin as to:

2. Layers of the epidermis

Clinical Correlation

 

     1.1. its specific layers

    2.1. Stratum corneum

 

Prelim Exam

     1.2. cellular components of each layer

    2.2. Stratum ludicum

Random Recitation

 

     1.3. sublayers

    2.3. Stratum granulosum

 

Midterm Exam

2. describe common clinical conditions

    2.4. Stratum spinosum

Laboratory exercises with

 

associated with the skin

    2.5. Stratum basale

slide orientation using

Final Exam

 

3. Cells of the epidermis

videoflex and iPad

 

 

    3.1. Keratinocytes

 

Practical Exams

 

    3.2. Langerhan's cell

Small group discussions

 

 

    3.3. Merkel's cell

 

 

 

4. Sublayer of the dermis

 

 

 

    4.1. Papillary layer

 

 

 

    4.2. Reticular layer

 

 

 

5. Common condition of the skin

 

 

 

    5.1. Pimples

 

 

 

    5.2. Alopecia

 

 

 

    5.3. Cutaneous wart

 

 

 

    5.4. Basal cell carcinoma

 

 

 

    5.5. Squamous cell carcinoma

 

 

 

    5.6. Melanoma

 

 

 

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            DEVELOPMENT OF THE CENTRAL NERVOUS SYSTEM

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Parts of the Central Nervous System that

2 hours lecture

Didactic lecture with

Short Quiz

 

develops the neural tube.

powerpoint presentations

 

1. describe the different parts of the central

    1.1. Prosencephalon

2 hours laboratory

 

Unit Quiz

nervous system that develops from the

    1.2. Mesencephalon

Clinical Correlation

 

neural tube.

    1.3. Phombencephalon

 

Prelim Exam

2. describe common congenital central

2. Common Central Nervous System defects

Random Recitation

 

nervous system defect.

    2.1. Anencephaly

 

Midterm Exam

 

    2.2. Meningocoele

Laboratory exercises with

 

 

    2.3. Meningoencephalocoele

slide orientation using

Final Exam

 

    2.4. Arnold Chiari Syndrome

videoflex and iPad

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            EXTERNAL AND INTERNAL FEATURES OF THE CEREBRUM

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Anatomical lobes of the cerebrum

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Frontal lobe

powerpoint presentations

 

1. describe the anatomical lobes of the

    1.2. Temporal lobe

2 hours laboratory

 

Unit Quiz

cerebrum

    1.3. Parietal lobe

Clinical Correlation

 

2. describe the major functional areas of the

    1.4. Occipital lobe

 

Prelim Exam

cerebrum

2. Amjor functional areas of the cerebrum

Random Recitation

 

 

    2.1. Motor center

 

Midterm Exam

 

    2.2. Sensory center

Laboratory exercises with

 

 

    2.3. Motor speech center

slide orientation using

Final Exam

 

    2.4. Motor association center

videoflex and iPad

 

 

    2.5. Sensory association center

 

Practical Exams

 

    2.6. Visual center

Small group discussions

 

 

    2.7. Auditory center

 

 

 

    2.8. Olfactory center

 

 

 

   2.9. Gustatory center

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            MENINGES, CSF, AND BLOOD BRAIN BARRIER

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. General characteristics of CSF

2 hours lecture

Didactic lecture with

Short Quiz

 

2. Functions of the CSF

 

powerpoint presentations

 

1. describe the characteristics of the CSF in

3. Formation of the CSF

2 hours laboratory

 

Unit Quiz

relation to:

    3.1. Structures involved in production

 

Clinical Correlation

 

    1.1. Physical apperance

    3.2. Pathway of CSF

 

 

Prelim Exam

    1.2. Composition

4. Components of the blood brain barrier

 

Random Recitation

 

2. discuss the functions of CSF.

5. Characteristics of the meninges of the brain

 

 

Midterm Exam

3. discuss the formation of CSF as to:

    5.1. Dura mater

 

Laboratory exercises with

 

    3.1. Structures that produce CSF

    5.2. Arachnoid mater

 

slide orientation using

Final Exam

          (cerebrospinal fluid)

    5.3. Pia mater

 

videoflex and iPad

 

    3.2. Pathway of CSF flow

6. Spaces between the meninges

 

 

Practical Exams

4. illustrate the blood-brain barrier and its

7. Dural venous sinuses

 

Small group discussions

 

components

 

 

 

 

5. describe the meninges of the brain and

 

 

 

 

the important spaces found between them

 

 

 

 

6. describe the different dural venous sinuses.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            DEVELOPMENT OF THE RESPIRATORY SYSTEM

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Embryological development of the respiratory tract

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Pharyngeal pouches and arches and the

 

powerpoint presentations

 

1. describe the development of the

           structures that developed from them.

2 hours laboratory

 

Unit Quiz

respiratory tract in relation to:

    1.2. Anlage of the respiratory tree.

 

Clinical Correlation

 

    1.1. the pharyngeal pouches and arhes,

    1.3. Development of the tracheoesophageal

 

 

Prelim Exam

      and the structures that developed

          septum.

 

Random Recitation

 

      from them.

2. Phases in the development of the respiratory tract

 

 

Midterm Exam

    1.2. germ layer/s of origin

3. Anoamlies associated with the development of the

 

Laboratory exercises with

 

2. describe the anlage of the respiratory tree.

respiratory tract.

 

slide orientation using

Final Exam

3. discuss the development of the trachea-

 

 

videoflex and iPad

 

esophageal septum.

 

 

 

Practical Exams

4. characterize each phase in the

 

 

Small group discussions

 

development of the respiratory tract.

 

 

 

 

5. discuss some anomalies associated with the development of the respiratory tract.

 

 

 

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            HISTOLOGY OF RESPIRATORY SYSTEM

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Histologic features of the nasal cavity,

2 hours lecture

Didactic lecture with

Short Quiz

 

paranasal sinuses and nasopharynx

 

powerpoint presentations

 

1. describe the histology of the nasal cavity

   1.1. Characteristics of the respiratory

2 hours laboratory

 

Unit Quiz

in relation to:

         epithelium and olfactory epithelium

 

Clinical Correlation

 

    1.1. lining epithelium

   1.2. Characteristics of the olfactory mucous

 

 

Prelim Exam

         1.1.1. respiratory epithelium

       membrane, mucoperiosteum or mucoperichon-

 

Random Recitation

 

         1.1.2. olfactory epithelium

       drium of the nasal cavity

 

 

Midterm Exam

    1.2. supporting structures

2. Characteristics of the mucous membrane of the

 

Laboratory exercises with

 

2. describe the mucous membrane of the

paranasal sinuses and nasopharynx

 

slide orientation using

Final Exam

paranasal sinuses.

3. Nasopharynx and the formation of the naso-

 

 

 

3. describe the nasopharynx and the

pharyngeal tonsil

 

videoflex and iPad

Practical Exams

formation of the nasopharyngeal tonsil.

4. Larynx 

 

 

 

4. compare the histologic features of the

   4.1. Subdivisions

 

Small group discussions

 

larynx and the trachea

   4.2. Cartilages

 

 

 

5. discuss the histology of the lungs

   4.3. Muscles and ligaments

 

 

 

and the intrapulmonary bronchial trees.

   4.4. Laryngeal glands

 

 

 

6. discuss the significance of surfactants and

5. Trachea

 

 

 

its role in the development of the Respiratory

    5.1. Lining epithelium

 

 

 

Distress Syndrome and hyaline Membrane

    5.2. Layers of the wall

 

 

 

Disease

6. Lungs and the intrapulmonary bronchial tree.

 

 

 

7. enumerate the structures forming the

    6.1. Different between the intrapulmonary

 

 

 

blood alveolar air barrier.

           bronchial tree and extrapulmonary

 

 

 

 

           bronchial tree and extrapulmonary

 

 

 

 

    6.2. Pulmonary alveoli

 

 

 

 

    6.3. Characteristics, origin  and function of

 

 

 

 

dust cells and clara cells

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            DEVELOPMENT OF THE URINARY SYSTEM

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Different kidney systems in urinary embryology

2 hours lecture

Didactic lecture with

Short Quiz

 

and their fates.

 

powerpoint presentations

 

1.illustrate by means of a diagram the

2. Derivatives of the permanent kidney.

2 hours laboratory

 

Unit Quiz

development of the urinary system

3. Formation of the nephron and collecting tubule

 

Clinical Correlation

 

2. differentiate the kidney systems in the

4. Formation of the ureter, urinary bladder and

 

 

Prelim Exam

developing fetus and their fates.

urethra

 

Random Recitation

 

3. explain how malformations/abnormalities

5. Common congenital anomalies of the urinary

 

 

Midterm Exam

associated with the development of the

system.

 

Laboratory exercises with

 

urinary system can occur.

 

 

slide orientation using

Final Exam

 

 

 

videoflex and iPad

 

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            HISTOLOGY OF THE URINARY SYSTEM

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Oragns of the urinary system and their functions

2 hours lecture

Didactic lecture with

Short Quiz

 

2. Macroscopic structures and regions of the

 

powerpoint presentations

 

1. list the organs of the urinary system

kidney and their functions

2 hours laboratory

 

Unit Quiz

2. describe the role of each organ in the

3. Components of the nephron

 

Clinical Correlation

 

system's functions

    3.1. Morphologic features

 

 

Prelim Exam

3. describe the structures and regions visible

    3.2. Location

 

Random Recitation

 

in the frontal section of the kidney and their

    3.4. Function of each components

 

 

Midterm Exam

functions

4. Components of the juxtaglomerular apparatus

 

Laboratory exercises with

 

4. describe the nephron as to structure,

and their functions

 

slide orientation using

Final Exam

function, location of each components, and

5. Vascular supply and drainage of the kidneys

 

videoflex and iPad

 

the histologic features of each components.

6. Physiology of urine formation.

 

 

Practical Exams

5. describe the components and function

 

 

Small group discussions

 

of the juxtaglomerular apparatus

 

 

 

 

6. trace the flow of blood through the kidney

 

 

 

 

7. identify the renal vascular elements in

 

 

 

 

histologic sections

 

 

 

 

8. discuss the physiology of urine formation

 

 

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            FORMATION OF PLACENTA

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Embryologic formation of the placenta

2 hours lecture

Didactic lecture with

Short Quiz

 

2. Placental implantation to the uterine wall

 

powerpoint presentations

 

1. describe how the placenta is formed

3. maternal and fetal components of the placenta

2 hours laboratory

 

Unit Quiz

2. illustrate the connection between the

and its functions

 

Clinical Correlation

 

embryo and the the placenta through the

4. Histologic components of the placenta

 

 

Prelim Exam

umbilical cord

5. types of decidua

 

Random Recitation

 

3. describe the parts of the placenta and

6. Placental Function in terms of blood supply,

 

 

Midterm Exam

their functions.

drainage and nutrition to the fetus

 

Laboratory exercises with

 

4. cite examples of abnormal placental

7. Illustration of abnormal placental formation

 

slide orientation using

Final Exam

formation

 

 

videoflex and iPad

 

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            DEVELOPMENT OF THE PRIMARY GERM LAYERS (GASTRULA)

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Formation of the primary germ layers

2 hours lecture

Didactic lecture with

Short Quiz

 

2. Formation of the embryonic disc

 

powerpoint presentations

 

1. discuss the foundation of the primary

3. Structures derived from the ectoderm,

2 hours laboratory

 

Unit Quiz

germ layers

mesoderm, endoderm

 

Clinical Correlation

 

2. describe the foundation of the parts of the

4.  Common abnormalities that occur during germ

 

 

Prelim Exam

embryonic disc

layer formation

 

Random Recitation

 

3. enumerate the derivatives of the three

 

 

 

Midterm Exam

germ layers

 

 

Laboratory exercises with

 

4. explain the effects of the occurrence of

 

 

slide orientation using

Final Exam

abnormalities during the formation of the

 

 

videoflex and iPad

 

different germ layers.

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            EXTERNAL AND INTERNAL FEATURES OF THE CEREBELLUM

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. External and internal features of the

2 hours lecture

Didactic lecture with

Short Quiz

 

cerebellum

 

powerpoint presentations

 

1. describe the general external and internal

2. Cerebellum hemispheres and vermis

2 hours laboratory

 

Unit Quiz

features of the cerebellum

    2.1 Lobules

 

Clinical Correlation

 

2. label the different lobules in the vermis

    2.2. Fissures

 

 

Prelim Exam

their corresponding parts in the cerebellar

    2.3. Location of cerebellar nuclei

 

Random Recitation

 

hemispheres, and the fissures separating

3. Cerebellar peduncles and their functions

 

 

Midterm Exam

them.

4. Common cerebellar lesions and their

 

Laboratory exercises with

 

3. describe the cerebellar peduncles and its

clinical manifestation

 

slide orientation using

Final Exam

functions.

 

 

videoflex and iPad

 

4. describe common clinical manifestations

 

 

 

Practical Exams

of cerebellar lesions

 

 

Small group discussions

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            GENERAL SENSORY AND MOTOR PATHWAYS

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Ascending pathways for general sensation

2 hours lecture

Didactic lecture with

Short Quiz

 

from the trunk and extremities

 

powerpoint presentations

 

1. identify the different components of the

    1.1 crude touch and pressure from the

2 hours laboratory

 

Unit Quiz

ascending pathway for following general

    1.2. crude pain and temperature

 

Clinical Correlation

 

sensations from the trunk and extremities

    1.3. discriminative touch and pressure

 

 

Prelim Exam

    1.1. Crude touch and pressure

    1.4. conscious proprioception

 

Random Recitation

 

    1.2. Pain and temperature

    1.5. unconscious proprioception

 

 

Midterm Exam

    1.3. Discriminative touch and pressure

2. Motor descending pathway of the pyramidal

 

Laboratory exercises with

 

    1.4. Proprioception (conscious)

tract.

 

slide orientation using

Final Exam

    1.5. proprioception (unconscious)

 

 

videoflex and iPad

 

2. identify the components of the pyramidal

 

 

 

Practical Exams

tract

 

 

Small group discussions

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            DIENCEPHALON

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Subdivisions of the diencephalon

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Components of the thalamus

 

powerpoint presentations

 

1. discuss the subdivision of the

    1.2. Parts of the hypothalamus

2 hours laboratory

 

Unit Quiz

diencephalon an d its parts

    1.3. Parts of the subthalamus

 

Clinical Correlation

 

2. describe the different thalamic nuclei and

    1.4. Parts of the epithalamus

 

 

Prelim Exam

their functions

2. Thalamic nuclei

 

Random Recitation

 

3. describe the different hypothalamic

3. Hypothalamis nuclei

 

 

Midterm Exam

nuclei  and their functions

4. Functions of the different subdivision

 

Laboratory exercises with

 

4. describe the functions of the different

of the diencephalon

 

slide orientation using

Final Exam

subdivisions of the diencephalon

 

 

videoflex and iPad

 

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            BASAL GANGLIA AND ITS CONNECTIONS

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Parts of the basal ganglia

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Functions of the different basal ganglia

 

powerpoint presentations

 

1. label the structures forming the basal

           components

2 hours laboratory

 

Unit Quiz

ganglia

    1.2. Role of basal ganglia components in the

 

Clinical Correlation

 

2. describe the functions of the component

           extrapyramidal system

 

 

Prelim Exam

structures of the basal ganglia and their

2. Clinical manifestations of the common basal

 

Random Recitation

 

role in the extrapyramidal system

ganglia lesions

 

 

Midterm Exam

3. describe common clinical manifestations

3. Fiber tract connections associated with basal

 

Laboratory exercises with

 

involving lesion of the basal ganglia

ganglia

 

slide orientation using

Final Exam

4. identify the fiber tracts connections

 

 

videoflex and iPad

 

associated with basal ganglia

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            DEVELOPMENT OF THE EYE

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Embryological formation of the different parts

2 hours lecture

Didactic lecture with

Short Quiz

 

of the eye

 

powerpoint presentations

 

1. describe the sequence of events in the

2. Common congenital anomalies associated

2 hours laboratory

 

Unit Quiz

development of the visual organs develop

with the development of the eye

 

Clinical Correlation

 

2. discuss the effects of malformation /

    2.1. How they develop

 

 

Prelim Exam

abnormalities in the development of the eye.

    2.2. Clinical effects

 

Random Recitation

 

 

 

 

 

Midterm Exam

 

 

 

Laboratory exercises with

 

 

 

 

slide orientation using

Final Exam

 

 

 

videoflex and iPad

 

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            SPECIAL SENSES: Vision or Sense of Sight

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Microscopic features of the coats of eyeball

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Fibrous coat

powerpoint presentations

 

1. describe the microscopic features of the

        1.1.1 histology of the cornea

2 hours laboratory

 

Unit Quiz

following coats of the eyeball:

        1.1.2. Histology of the sclera

Clinical Correlation

 

    1.1. Fibrous Coat

    1.2. Vascular/Muscular coat (UVEA)

 

Prelim Exam

         1.1.1. Cornea        1.1.2. Sclera

        1.2.1. Histology of the choroid

Random Recitation

 

    1.2. vascular/Muscular Coat (UVEA)

        1.2.2. Histology of the ciliary body

 

Midterm Exam

         1.2.1. Choroid       1.2.3. Iris

        1.2.3. Histology of the iris

Laboratory exercises with

 

         1.2.2. Cilisry body

    1.3. Nervous coat

slide orientation using

Final Exam

    1.3. Nervous Coat

        1.3.1. Histology of the retina

videoflex and iPad

 

         1.3.1. Retina

2. Structures included in the refractve media of

 

Practical Exams

2. describe the refractive media of the eyes

the eyes

Small group discussions

 

3. illustrate with a diagram the pathway of

3. Formation of the aqueous humor from the

 

the aqueous humor site of formation

ciliary process and pathway towards its drainage

 

 

to its drainage

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            VISUAL PATHWAY

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Structures involved in the visual pathway from

2 hours lecture

Didactic lecture with

Short Quiz

 

the retina to the visual cortex

powerpoint presentations

 

1. identify the different type of visual

2.Clinical disorders associated with visual field

2 hours laboratory

 

Unit Quiz

pathway from the retina to the visual cortex

injury/lesion and the corresponding visual field

Clinical Correlation

 

2. Illustrate the visual field defects arising

defects

 

Prelim Exam

from lesions/injury along the visual pathway

 

Random Recitation

 

 

 

 

Midterm Exam

 

 

Laboratory exercises with

 

 

 

slide orientation using

Final Exam

 

 

videoflex and iPad

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            VISUAL REFLEX AND EYE MOVEMENTS

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Visual refles pathway

2 hours lecture

Didactic lecture with

Short Quiz

 

     1.1. Structures involved in the visual pathway

powerpoint presentations

 

1. discuss visual reflex and eye movements

     1.2. Clinical significance of visual reflexes

2 hours laboratory

 

Unit Quiz

2. give the clinical importance of visual

2. Stimuli involved in accomodation of

Clinical Correlation

 

reflexes

convergence reflex

 

Prelim Exam

3. explain how accomodation convergence

 

Random Recitation

 

reflex is elicited

 

 

Midterm Exam

 

 

Laboratory exercises with

 

 

 

slide orientation using

Final Exam

 

 

videoflex and iPad

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            SPINAL REFLEX ARC AND ITS CLASSIFICATION

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Structures involved in the spinal reflex

2 hours lecture

Didactic lecture with

Short Quiz

 

2. Types of spinal reflexes

powerpoint presentations

 

1. differentiate the types of spinal reflexes

    2.1. somato-somatic spinal reflex

2 hours laboratory

 

Unit Quiz

2. label the parts of a refles arc.

    2.2. somato-visceral spinal reflex

Clinical Correlation

 

3. classify spinal reflexes

    2.3. viscero-somatic spinal reflex

 

Prelim Exam

 

    2.4. viscero-visceral spinal reflex

Random Recitation

 

 

 

 

Midterm Exam

 

 

Laboratory exercises with

 

 

 

slide orientation using

Final Exam

 

 

videoflex and iPad

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            LIMBIC SYSTEM

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Parts of the limbic system

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Components in the cerebral cortex

powerpoint presentations

 

1. describe the component parts of the

    1.2. Components in the diencephalon

2 hours laboratory

 

Unit Quiz

limbic system together with their functions

2. Functions of the limbic system

Clinical Correlation

 

2. give the functional significance of Papez

3. Papez circuit

 

Prelim Exam

Circuit

 

Random Recitation

 

 

 

 

Midterm Exam

 

 

Laboratory exercises with

 

 

 

slide orientation using

Final Exam

 

 

videoflex and iPad

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            RETICULAR-ACTIVATING SYSTEM

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Components of the Reticular Activating

2 hours lecture

Didactic lecture with

Short Quiz

 

System

powerpoint presentations

 

1. describe the anatomical components of

2. List of functions of the RAS

2 hours laboratory

 

Unit Quiz

the Reticular Activating System

3. Clinical significance of the RAS

Clinical Correlation

 

2. give the functions of the Reticular

 

 

Prelim Exam

Activating System

 

Random Recitation

 

3. give the clinical significance of the

 

 

Midterm Exam

Reticular Activating System

 

Laboratory exercises with

 

 

 

slide orientation using

Final Exam

 

 

videoflex and iPad

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            VESTIBULAR APPARATUS

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Histological features of the vestibular

2 hours lecture

Didactic lecture with

Short Quiz

 

apparatus

powerpoint presentations

 

1. describe the histological features of the

     1.1. Macula, insula and utricle

2 hours laboratory

 

Unit Quiz

vestibular apparatus

     1.2. Cristae ampullaris in semicircular canals

Clinical Correlation

 

2. enumerate the receptors and supporting

2. Receptor and supporting cells of maculae

 

Prelim Exam

cells of the vestibular apparatus

and cristae ampullaris

Random Recitation

 

3. describe the production site and location

3. Production site and location of perilymph

 

Midterm Exam

of perilymph and endolymph

and endolymph

Laboratory exercises with

 

 

 

slide orientation using

Final Exam

 

 

videoflex and iPad

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            VESTIBULAR PATHWAY

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Components of vestibular pathway

2 hours lecture

Didactic lecture with

Short Quiz

 

   1.1. structures involved in the ascending and

powerpoint presentations

 

1. enumerate the components of the

        descending portion of the vestibular

2 hours laboratory

 

Unit Quiz

vestibular pathway

        pathway

Clinical Correlation

 

2. trace the vestibular pathway from the

   1.2. receptors for balance and their location

 

Prelim Exam

receptor to the center and its descending

   1.3. terminal structures of vestibular pathway

Random Recitation

 

pathways

        and its projections

 

Midterm Exam

3. describe the receptors for balance and

2. Physiology of the propagation of action

Laboratory exercises with

 

their location

potential from  the vestibular receptors

slide orientation using

Final Exam

4. explain how the receptors are stimulated

3. Clinical significance of vestibular pathway

videoflex and iPad

 

to propagate action potential to the rest of

4. Principles involved in the various test for the

 

Practical Exams

the nerve fibers

vestibular pathway

Small group discussions

 

5. discuss the termination of the vestibular

5. Clinical symptoms of common vestibular

 

 

pathway and its various projection

system disorders.

 

 

6. discuss the importance of vestibular

 

 

 

pathway in our daily activities

 

 

 

7. demonstrate the test for vestibular

 

 

 

system

 

 

 

8. correlate the symptoms associated with

 

 

 

disorder of the vestibular system and the

 

 

 

pathway

 

 

 

 

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            DEVELOPMENT OF SPECIAL SENSES: EAR, TASTE, OLFACTORY

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Embryology of the special senses

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Embrology of the tongue

powerpoint presentations

 

1. describe the development of the

    1.2. Embryology of the nos and nasal cavity

2 hours laboratory

 

Unit Quiz

ears, tongue and nose

    1.3. Embryology of the ears

Clinical Correlation

 

2. discuss how malformations/abnormalities

2. Common congenital anomalies associated with

 

Prelim Exam

associated in the development of the

the tongue, nose and ears

Random Recitation

 

special sense can occur

 

 

Midterm Exam

 

 

Laboratory exercises with

 

 

 

slide orientation using

Final Exam

 

 

videoflex and iPad

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            SPECIAL SENSE: Hearing or Auditory Sense

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Three main parts of the ear

2 hours lecture

Didactic lecture with

Short Quiz

 

   1.1. External ear

powerpoint presentations

 

1. describe the microscopic parts and

   1.2. Middle ear

2 hours laboratory

 

Unit Quiz

features of the ear

   1.3. Inner ear

Clinical Correlation

 

2. differentiate between bony and

2. Differences between bony and membranous

 

Prelim Exam

membranous labyrinths according to

Labyrinths

Random Recitation

 

divisions, fluid contents, receptor areas,

3. Histology of the semicircular duct, utricle, and

 

Midterm Exam

ganglia and peripheral nerves involved.

saccule

Laboratory exercises with

 

3. describe the microscopic features of the:

4. Flow of endolymph during sound conduction

slide orientation using

Final Exam

   3.1. semicircular duct

5. Illustration of the bony cochlea

videoflex and iPad

 

   3.2. utricle

6. Histology of the cochlear duct

 

Practical Exams

   3.3. saccule

7. pathway of sound transmission

 

Small group discussions

 

 

 

 

4. explain the movement of endolymph in

 

 

 

 

semicircular duct

 

 

 

5. describe the bony cochlea

 

 

 

6. discuss the microscopic features of the

 

 

 

cochlear duct

 

 

 

7. discuss the mechanism of hearing

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            SPECIAL SENSE: Olfactory, Taste

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Olfactory mucosa

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Histology of the olfactory mucosa

powerpoint presentations

 

1. describe the microscopic anatomy of the

    1.2. Differences between the olfactory mucosa

2 hours laboratory

 

Unit Quiz

olfactory mucosa

          and the respiratory mucosa

Clinical Correlation

 

2. differentiate between olfactory mucosa

    1.3. Cells of the olfactory epithelium

 

Prelim Exam

and respiratory mucosa

    1.4. Clinical significance of the Bowman's

Random Recitation

 

3. name the cells comprising the olfactory

           gland

 

Midterm Exam

nueroepithelium

2. Taste bud

Laboratory exercises with

 

4. explan the functional significance of the

    2.1. Histology of the taste bud

slide orientation using

Final Exam

serous gland of Bowman

    2.2. Cells in the epithelium of the taste bud

videoflex and iPad

 

5. describe the microscopic features of the

    2.3. Diagnostic illustration of a taste bud and

 

Practical Exams

taste bud

          its nerve supply

Small group discusions

 

6. Illustarte diagrammatically the taste bud

 

 

 

and its nerve supply

 

 

 

 

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            DEVELOPMENT OF ENDOCRINE SYSTEM

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Embryology of the different endocrine organs

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Germ layers of origin

powerpoint presentations

 

1. describe the formation of the different

    1.2. Anlage

2 hours laboratory

 

Unit Quiz

endocrine organs in relation to:

    1.3. Important events

Clinical Correlation

 

    1.1. germ layer of origin

2. Hormones secreted by each endocrine organ

 

Prelim Exam

    1.2. anlage

3. Common clinical conditions associated with

Random Recitation

 

    1.3. highlights in development

abnormal development of endocrine system

 

Midterm Exam

2. give the different hormones produced by

    3.1. Pharyngeal hypophysis

Laboratory exercises with

 

these organs

    3.2. Craniopharyngioma

slide orientation using

Final Exam

3. recognize clinical effects of some clinical

    3.3. Ectopic thyroid

videoflex and iPad

 

conditions associated with abnormal

    3.4. Annular pancreas

 

Practical Exams

development of these organs

    3.5. Pancreatic rest

 

Small group discusions

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            ENDOCRINE SYSEM

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Histologic features of the different endocrine

2 hours lecture

Didactic lecture with

Short Quiz

 

organs mwith their corresponding secretions

powerpoint presentations

 

1. discuss the different endocrine organs,  in

    1.1. Pituitary                   1.5. Adrenal

2 hours laboratory

 

Unit Quiz

relation to its:

    1.2. Pineal                      1.6 Pancreas

Clinical Correlation

 

    1.1. Histologic features

    1.3. Thyroid                    1.7. Testes

 

Prelim Exam

    1.2. Functions

    1.4. Parathyroid              1.8. Ovary

Random Recitation

 

    1.3. Hormonal secretions and their

2.Manifestations of patients with endocrine

 

Midterm Exam

         mechanisms of action

organs malfunction

Laboratory exercises with

 

2. Correlate the clinical manifestation with

   2.1. Hyperfunctioning endocrine gland

slide orientation using

Final Exam

hyper- or hypofunctioning od the endocrine

   2.2. Hypofunctioning endocrine glands

videoflex and iPad

 

system

 

 

Practical Exams

 

 

 

Small group discusions

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            LESIONS OF SPINAL CORD

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Features of different levels of the spinal cord

2 hours lecture

Didactic lecture with

Short Quiz

 

2. Structures of spinal cord involved in the

powerpoint presentations

 

1. discuss the anatomical bases of the signs

following clinical conditions with their

2 hours laboratory

 

Unit Quiz

and symptoms of injuries to different parts

manifestations

Clinical Correlation

 

and levels of the spinal cord

    2.1. Broen Sequard

 

Prelim Exam

2. identify the parts of the spinal cord injured

    2.2. Poliomyelitis

Random Recitation

 

in the following clinical conditions, and their

    2.3. Syringomyelitis

 

Midterm Exam

clinical features.

    2.4. Tabes dorsalis

Laboratory exercises with

 

   2.1. Brown-Sequard Syndrome

    2.5. Amyotrophic lateral sclerosis

slide orientation using

Final Exam

   2.2. Poliomyelitis

    2.6. Subacute combined degeneration

videoflex and iPad

 

   2.3. Syringolyelia

 

 

Practical Exams

   2.4. tabes dorsalis

 

Small group discussions

 

   2.5. Amyotrophic lateral sclerosis

 

 

 

   2.6. Subacute combined degeneration

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            INTERNAL AND EXTERNAL FEATURES OF THE BRAINSTEM

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. External parts of the brainstem

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. Anterior structures of the brainstem

powerpoint presentations

 

1. enumerate the different parts of the

    1.2. Posterior structures of the brainstem

2 hours laboratory

 

Unit Quiz

brainstem

2. Internal parts of the brainstem

Clinical Correlation

 

2. describe the internal parts of the

    2.1. Internal structures of the midbrain

 

Prelim Exam

brainstem

    2.2. Internal structures of the pons

Random Recitation

 

 

    2.3. Internal structure of the medulla oblongata

 

Midterm Exam

 

 

Laboratory exercises with

 

 

 

slide orientation using

Final Exam

 

 

videoflex and iPad

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            LESIONS OF THE BRAINSTEM

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

Brianstem lesions and their clinical

2 hours lecture

Didactic lecture with

Short Quiz

 

manifestations:

powerpoint presentations

 

1. discuss the anatomical bases of the

1. Medial basal midbrain

2 hours laboratory

 

Unit Quiz

different clinical conditions involving

2. Tegmentum of midtbrain

Clinical Correlation

 

lesions of the brainstem

3. Tectum of the midbrain

 

Prelim Exam

2. Correlate the clinical manifestations of the

4. Lateral Lower pons

Random Recitation

 

conditions with anatomic structures

5. Medial lower pons

 

Midterm Exam

involved in the lesions

6. Medial basal upper medulla oblongata

Laboratory exercises with

 

 

7. Posterolateral upper medulla

slide orientation using

Final Exam

 

 

videoflex and iPad

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            EVENTS IN FERTILIZATION

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Histological changes of the ovum from

2 hours lecture

Didactic lecture with

Short Quiz

 

fertilization to uterine implantation

powerpoint presentations

 

1. describe the different events that happen

2. Process of blastocyst implantaion in the

2 hours laboratory

 

Unit Quiz

during fertilization in relation to:

endometrium

Clinical Correlation

 

   1.1. changes undergone by the fertilized

3. Clinical condition associated with abnormal

 

Prelim Exam

        ovum as it passes dowm from the

blastocyst implantation

Random Recitation

 

       uterine cavity for implantation

 

 

Midterm Exam

   1.2. implantation of the blastocyst into the

 

Laboratory exercises with

 

        compact layer of the endometrium of

 

slide orientation using

Final Exam

        the uterus.

 

videoflex and iPad

 

2. cite the clinical conditions that occur

 

 

Practical Exams

when the blastocyts implant elsewhere

 

Small group discussions

 

other than the uterine wall.

 

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            MALE REPRODUCTIVE SYSTEM

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Male reproductive system

2 hours lecture

Didactic lecture with

Short Quiz

 

    1.1. histology of the male reproductive system

powerpoint presentations

 

1. describe the specific light microscopic

    1.2. Primary and secondary male reproductive

2 hours laboratory

 

Unit Quiz

structures of male reproductive organs

          organs

Clinical Correlation

 

2. categorize the male reproductive organs

2. Spermatogenesis

 

Prelim Exam

into primary and secondary organs

    2.1. Phases of spermatogenesis

Random Recitation

 

3. discuss the phases of spermatogenesis

    2.2. Processes involved in sperm capacitation

 

Midterm Exam

4. describe the other cell/s seen inside the

3. Cells in the spermatogenic apithelium

Laboratory exercises with

 

testis and their functions

4. Histological features of the testicular ducts

slide orientation using

Final Exam

5. state the specific histologic structures

and its functions

videoflex and iPad

 

that contribute to the function of the

5. Male reproductive accessory organ and

 

Practical Exams

Sertoli cell

secretions

Small group discussions

 

6. describe the duct system of the male

6. Histology of erectile tisue

 

 

reproductive organ

7. Histology of spermatic cord

 

 

7. compare histologic features of the intra-

 

 

 

 and extratesticular ducts and their

 

 

 

contributions to the viability and normal

 

 

 

transport of the mature sperm

 

 

 

8. differentiate the histologic features of the

 

 

 

accessory organs of the male reproductive

 

 

 

system and its secretions that contribute to

 

 

 

the normal characteristic of semibal fluid.

 

 

 

9. decsribe the histologic features of erectile

 

 

 

tissue

 

 

 

10. describe the histologic features of the

 

 

 

spermatic cord

 

 

 

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            FEMALE REPRODUCTIVE SYSTEM

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Hstology of femlae reproductive system

2 hours lecture

Didactic lecture with

Short Quiz

 

   1.1 Ovary

powerpoint presentations

 

1. discuss the specific light microscopic

   1.2. Fallopian tube

2 hours laboratory

 

Unit Quiz

features of the different organs of the

   1.3. Uterus

Clinical Correlation

 

female reproductive system

   1.4. Vagina

 

Prelim Exam

2. describe histologically the development of

   1.5.Clitoris

Random Recitation

 

the ovarian follicles

   1.6. Mammary gland

 

Midterm Exam

3. compare the histological changes in the

2. Histological development of the ovarian

Laboratory exercises with

 

ovary during menstruation, pregnancy and

follicles

slide orientation using

Final Exam

menopause

3. Histological changes of the ovary during

videoflex and iPad

 

4. describe the histologic changes of the

menstrual cycle, pregnancy, and menopause

 

Practical Exams

other components of the female

4. Structural features of the oviduct in relation to

Small group discussions

 

reproductive system during the menstrual

menstruation and pregnancy

 

 

cycle and pregnancy

5. Histologic features of the endometrium

 

 

5. describe the histology of the erectile and

during proliferative phase, menstrual phase and

 

 

nervous tissues of the clitoris

pregnancy

 

 

6. discuss the characteristic histology of the

6. Histology of the ectocervix and endocervix

 

 

mammary gland in relation to the stages of

during menstrual cycle and pregnancy

 

 

female growth and development

7. Cytology of the vaginal epithelium during the

 

 

 

different phases of menstrual cycle

 

 

 

8. Histology of the erectile and nervous tissue of

 

 

 

the clitoris

 

 

 

9. Histology of the mammary gland in relation to

 

 

 

the stages of female growth and development

 

 

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            DEVELOPMENT OF MALE REPRODUCTIVE SYSTEM

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Embryology of the testes and its ducts

2 hours lecture

Didactic lecture with

Short Quiz

 

2. Embryology of the male external genitalia

powerpoint presentations

 

1. discuss embryologic development of

3. Embryology of the genital ducts in male and

2 hours laboratory

 

Unit Quiz

the components of the male reproductive

their fates

Clinical Correlation

 

system

4. Congenital anomalies of the male reproductive

 

Prelim Exam

2. explain how malformations or

system

Random Recitation

 

abnormalities in the development of the

 

 

Midterm Exam

male reproductive system can occur.

 

Laboratory exercises with

 

 

 

slide orientation using

Final Exam

 

 

videoflex and iPad

 

 

 

 

Practical Exams

 

 

 

Small group discussions

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            GAMETOGENESIS: SPERMATOGENESIS AND OOGENESIS

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Stages in spermatogenesis

2 hours lecture

Didactic lecture with

Short Quiz

 

   1.1. Clinical significance of meiosis I and

powerpoint presentations

 

1. describe the different stages in

       meiosis II in spermatogenesis

2 hours laboratory

 

Unit Quiz

spermatogenesis

   1.2. Common chromosomal abberations and its

Clinical Correlation

 

2. Give the significance of the two

       clinical manifestation

 

Prelim Exam

maturation divisions (meiosis I and meiosis II)

2. Stages in oogenesis

Random Recitation

 

undergone by the developing

   2.1. Clinical significance of meiosis I and

 

Midterm Exam

spermatogenic cells

       meiosis II in oogenesis

Laboratory exercises with

 

3. Give the clinical significance of

   2.2. Differences between spermatogenisis and

slide orientation using

Final Exam

chromosomal aberrations or abnormalities

       oogenesis

videoflex and iPad

 

and their causes.

 

 

Practical Exams

4. Enumerate the successive stages in the

 

 

Small group discussions

 

 

 

 

development of a mature human ovum

 

 

 

 

during oogenesis

 

 

 

5. Describe the different stages in oogenesis

 

 

 

6. Give the significance of the two

 

 

 

maturation divisions (meiosis I and meiosis II)

 

 

 

undergone by the developing oogonia

 

 

 

7. Differentiate spermatogenesis and

 

 

 

oogenesis

 

 

 

 

 

LEARNING OBJECTIVES

LEARNING CONTENT                            DYSFUNCTION OF THE CEREBRAL CORTEX

TIME ALLOTMENT (Hours)

TEACHING STRATEGIES

ASSESSMENT and  EVALUATION

At the end of the topic, the student can:

1. Functional areas of the cerebral cortex

2 hours lecture

Didactic lecture with

Short Quiz

 

   1.1. Signs and symptoms of lesion of the

powerpoint presentations

 

1. discuss the anatomical bases of the

         Broadmann's area 4

2 hours laboratory

 

Unit Quiz

different lesions involving the various parts

   1.2. Sign ands symptoms of lesion of premotor

Clinical Correlation

 

of the berebral cortex

         cortex

 

Prelim Exam

2. identify thef unctional areas of the

   1.3. Signs and symptoms of lesions of the

Random Recitation

 

cerebral cortex

         prefontal cortex

 

Midterm Exam

3. discuss the signs and symptoms  in

   1.4. Signs and symptoms of lesions of BA area

Laboratory exercises with

 

patients with lesions involving the

         44 & BA area 45

slide orientation using

Final Exam

following parts of the frontal lobe.

2. Lesions in specific areas of parietal lobe

videoflex and iPad

 

   3.1. Broadmann's area 4

    2.1. Signs and symptoms of lesions

 

Practical Exams

   3.2. Premotor cortex

         involving of Broadmann's area 3,1,2

Small group discussions

 

   3.3. Prefrontal cortex

    2.2. Signs and symptoms of lesions involving

 

 

   3.4. Broadmann's area 44 and 45

         the posterior parietal asociation area

 

 

4. Explain the effects of lessions in the

    2.3. Signs and symptoms of lesions in the

 

 

different part of the parietal lobe:

         Wernicke's area

 

 

   4.1. Broadmann's area 3,1,2

 

 

 

   4.2. Posterior parietal association areas

 

 

 

   4.3. Wernicke's area

 

 

 

 

 

 

 

 

  1. TEACHING /LEARNING STRATEGIES
  2. Lecture
  3. Recitations
  4. Demonstration
  5. Laboratory Exercises-anatomical models, preserved specimen or dissected cadavers
  6. Video presentation of certain topics

 

  1. EVALUATION/ASSESSMENT
  2. 1ST SEMESTER 40%
  3. 2ND SEMESTER 60%
  4. Each semestral grade is computed as follows:

                        Short Quizzes              10%

                        Unit Quizzes               15%

                        1st Prelims                    15%

                        2nd Prelims                   25%

                        Finals                           35%

                                                            100%

                        DIRECTLY ADDED POINTS:

                        Laboratory Manual     5%

                        Attendance                 2.5%

                        SGD                            5%

 

 

 

 

 

 

 

 

  1. TEXTBOOK & REFERENCES

Textbook:

Junquiera, Luis Carlos. Basic Histology, 13th ed. New York: Lange Medical Books, 2003,

Wheater, Paul Richad. Wheater’s Functional Histology: A Text and Color Atlas. Edinburgh: Churchill Livingstone, 2002

 

References:

Barne, Robert M. ed. Rubin’s Pathology: Clinicopathologic Foundations of Medicine. 4th ed. Philadelphia: Lippincott, 2005.

Cochard, Larry R. Netter’s Atlas of Human Embryology. New Jersey: Icon Learning Systems, 2002

Cormack, David H. Ham’s Histology, 9th ed. Philadelphia: Lippincott, 1987.

 

Department’s Lecture and Laboratory Guide.

Eroschenko, Victor P. DiFiore’s Atlas of Histology with Functional Correlations. 10th edition. Philadelphia: Lippincott, 2005

Fawcett, Don W. Bloom and Faucett’s Concise Histology, 2nd ed. London: Arnold Publications, 2002

Gartner, Leslie P. Cell Biology and Histology. 4th ed. Philadelphia: Lippincott, 2003

Gartner, Leslie P. Color Textbook of Histology, Philadelphia: Saunders, 2001

Junquiera, Carneiro, Kelly. Basic Histology, 10th edition. New York: Lange Medical Books, 2003

Kessel, Richard G. Basic medical Histology: The Biology of cells, Tissues and Organs :New York: Oxford University, Pres, 1998

Smith, Sarah Kay. Head and Neck Histology and Anatomy: A Self—Instructional Program. CT:Appleton and Lange, 2000

Fawxett, Don W. Bloom and Fawcett: Concise Histology. SI: Chapman and Hall, 1997.

           

Prepared by:                                                                Noted                                                              Approved by:

LUZVIMINDA S. SURIO, MD                                REMEDIOS P. SANTOS, MD                      REYNALDO A. OLAZO, MD

Chairman                                                                     Chair, Curriculum Committee                        Dean

 

ALBERT G. GIRONELLA, MD

Coordinator

 

CHONA H. ARAGA, MD

Faculty

Course Summary:

Date Details Due